@nina1944 Side effects vary, but I would say the most prevalent and for the most people seem to be scratchy voice and/or loss of voice which come back after stopping it. There are many side effects, but not everyone experiences them. Additionally, practicing “mindfulness as medicine” can help as well. One of the reasons Arikayce is recommended is because of patients who have difficulty with the Big 3 and/or do not achieve negative MAC sputum results. You know your body best. With that said, MAC is progressive for most people. There comes a time when we have to weigh the pros and cons of treatment options. In the research statistics, Arikayce appears to have good outcomes. irene5

@nina1944 Hi My side effects from Arikayce were minimal also, just a hoarse voice which improved over time and with strepfen, and a bit of a cough when I stat inhaling, just have a glass of water near by. It is great stuff!