← Return to Peripheral Hyper sensitization Neuropathy

Discussion

Peripheral Hyper sensitization Neuropathy

Neuropathy | Last Active: Feb 29 3:22pm | Replies (8)

Comment receiving replies
@johnbishop

@reno10, I did find some research that seems to explain your diagnosis some but I'm not sure.

"peripheral sensitization—hyperexcitability of sensory neurons due to lowered threshold and augmented response to suprathreshold stimuli, caused by peripheral nerve or tissue injury, inflammation and subsequent release of pro-nociceptive mediators from mast cells, macrophages and from neighbouring nerve terminals, such ..."
--- Peripheral Mechanisms of Neuropathic Pain—The Role of Neuronal and Non-Neuronal Interactions and Their Implications for Topical Treatment of Neuropathic Pain: https://www.mdpi.com/1424-8247/14/2/77

I wonder if you might find this discussion started by @rwinney helpful:
--- Central Sensitization - please share your stories: https://connect.mayoclinic.org/discussion/central-sensitization-please-share-your-stories/

Jump to this post


Replies to "@reno10, I did find some research that seems to explain your diagnosis some but I'm not..."

Thanks so much
I’ll check it out