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What happens after Tymlos?

Osteoporosis & Bone Health | Last Active: Sep 22 4:42pm | Replies (66)

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@formisc

Not surprising that the paper is filled with positives about Prolia while neglecting to mention much about the negatives.

Under the "Conflict of Interest Statement" section:
"OT has received fees from Amgen, GSK, Lilly, Nycomed, MEDA and Takeda as lecturer, consultant and/or scientific advisor."

Also, the report is from 2015 when many of the studies on the rebound effect were not out yet

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Replies to "Not surprising that the paper is filled with positives about Prolia while neglecting to mention much..."

It's also hard to understand why the rebound effect was not noticed in those early studies. It doesn't seem like it would be hidden. I mean you take Prolia for 3 years in a trial. You stop. Then, if you are one of what ever percent this happens to, you start fracturing like crazy. How would that not be noticed? I don't know why it wasn't but it does not seem logical. The rebound effect is not something that takes 10 years to develop like say a cancer might develop many years after a pesticide exposure. It's crazy quick.