My mom and grandfather suffered with it. No one knew what it was but with a lot of research we finally digit out ourselves. I have tried topical creams that were made by a pharmacist, Lyrica and gabapentin. Plus I have taken all types of magnesium Nothing has really ever worked for me. My mother was tremendously helped with Lyrica. And she was the most affected of us all. My daughter is now 40 and having symptoms. I pray for a cure!!