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Letrozole: When will I start feeling/seeing side effects?

Breast Cancer | Last Active: Apr 17 5:23pm | Replies (127)

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@windyshores

@ellerbracke I took the full 2.5mg every day for 5 years. My doc was okay with a half dose but I continued on the full dose. I would love info on whether reducing dose even makes a difference in terms of side effects because effectiveness depends on suppressing estrogen, regardless of dose, and that is what causes side effects. So whether 1.25mg or 2.5mg or even 0.5mg I would think the side effects would be the same. But I don't know.

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Replies to "@ellerbracke I took the full 2.5mg every day for 5 years. My doc was okay with..."

Stands to reason. It’s the fillers that can cause unwanted side effects beyond estrogen suppression effects. I have now taken the Anastrozole brand Arimidix and side effects much less ( hardly at all) which is a change as I had mild to moderate joint stiffness and discomfort ( which I mitigated by yoga and walking/hiking) insomnia and night sweats . Now much milder in all areas. SAME amt. of drug, 1mg Anastrozole