As I am at 20 months of taking prednisone, and only 4 and a half weeks in on the leflunomide, I can't really say if I will experience more side effects at this point. I have overcome afternoon nausea and AM headaches that occured at about week one but subsides by week 3. I did not feel any change until about week 3 and a half of the leflunomide. But the decrease in my pain and swelling has been profound this past week. I anticipate further improvement as leflunomide is a long term medication that takes 4-6 weeks to become effective with 3 months showing the full potential. (As per my rheumatologist) at this point I am remaining hopeful.
If you feel well at this time I would certainly discuss this with your rheumatologist. I have not tried methotrexate, but I understand it is the preferred drug of choice and has good outcomes also. I was limited as to my options.
I will be interested as to the reasoning for the switch, yes, given the reported adverse reactions to LF. I have lost weight also, but try to make good food choices, increased protein and I stay active.
All the best to you.

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