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PSA & MRI suspicious but biopsy benign
Prostate Cancer | Last Active: Mar 1 7:18pm | Replies (36)Comment receiving replies
I had PIRAD 4 and PIRAD 5 lesions that were both 3+3 Gleason upon TRUS targeted fusion biopsy.
As far as I know, the PIRAD scoring system doesn’t tell you anything about the aggressiveness of your PCa. It certainly didn’t in my case.
Instead of subjecting yourself to additional biopsies, with such a favorable initial biopsy result, you may want to ask your doc about the genomic ExoDx test. It only requires a urine sample to perform the test.
ExoDx test has Level 1 evidence, based on a 1000+ patient study, with a 91 % Negative Predictive Value (much higher than the PSA test). It designed to indicate the likelihood of GG2 (or greater) PCa. I’m going to ask to have this done before deciding on having my next biopsy, due in October.
ExoDx test is covered by Medicare.
You can read much more about it (including study trial paper) here:
https://www.exosomedx.com/physicians/exodx-prostate-test
Replies to "I had PIRAD 4 and PIRAD 5 lesions that were both 3+3 Gleason upon TRUS targeted..."
Thanks for info. My urologist didn’t mention urine ExoDX so I will ask internist to do
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I did do the ExoDx urine test before biopsy. My score is 18.77. Normal range is 0 - 15.6. Mine is a little higher the normal upper range. My Urologist mentioned this score to me, and I believe he accounted for this information before he recommends the biopsy.