I have taken Cymbalta for many years. I believe it helps me with pain sensations in my brain, where most pain originates. That is why it is given to people with pain, to my understanding. It is not a magic pill, as none of them are. It is a tool in my toolbox of things I do or take, to help combat my body wide pain. Progressive muscle relaxation, deep belly breathing, and tapping are more of my tools. I hope this helps you.