Ditto the research commenters have done so far in helping us understand this new chemotherapy. I’m wondering @robee when you said you had G|A; does that mean you didn’t receive the cis? I’ve had 4 treatments so far and I’ve had my hair fall out, sensitive digestion (avoid spicy food and/or eating too much per meal is the remedy for me), and extreme nausea. I had 5FU post surgery last year and didn’t have any symptoms except hair thinning and some nausea for about 2-3 days however my cancer metastasized about 4.5 months after I completed my 12 cycles of 5FU. I’m 66 years old. I mention age since it appears to me from reading postings that age (and obviously health status) correlates with one’s ability to handle chemo. I ask about the cisplatin because it seems to be one of the ingredients that my cancer is slowly responding to. Obviously the type of mutations you have ate also relevant so I’ll mention that you have an atm like mutation and the TP53. I don’t see any postings from others about TP53 and mention it because I believe it’s one of the real buggar mutations that makes complete recovery a challenge.