1. < Osteoporosis & Bone Health

Do we know the effects of Forteo & Tymlos on the femoral neck?

Posted by rogerscott8562 @rogerscott8562, Feb 10 12:56am

My T scores are -2.9 and -3.4. A fracture would be devastating.

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rogerscott8562 | @rogerscott8562 | Feb 12 12:19pm

For men and women who took steroids that caused BMD to decline, the average increase in BMD in 18 months was 3.7% at the femoral neck in the FDA approved trials for Forteo. For men it was 1.5% over 18 months. Here is link for FDA trial results for Forteo:
https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/021318s053lbl.pdf.
You can read trial results by searching for: FDA trial prescribing information for the particular drug. It helps a lot to read these before you get the document glued to the prescription box after it has been prescribed. I summarized the results in a spreadsheet but I can't find a way to show it here in readable form or using the add file option. If you wish to see my spreadsheet, give me your email address and I will email it to you. It has data for men and persons with osteoporosis caused by steroid drugs. I have narrowed my preferences to Prolia and Tymlos. Evenity is too risky if you want to live for more than a few years. Forteo requires a refrigerator making it difficult to travel.

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gravity3 | @gravity3 | Feb 13 7:13am
In reply to @hopefullibrarian "Hi Candy, During the summit in early January interviews were made available to view for free..." + (show)
@hopefullibrarian

Hi Candy,
During the summit in early January interviews were made available to view for free over a seven day period. Approximately 10 recorded interviews were made available per day, and only for that day. That's when I watched a large number of them, and took lots of notes. Post-summit it costs --$79 to have unlimited access to all of them, indefinitely. Here's the link: https://morebonehealth.byhealthmeans.com/?idev_id=30380
Most of the same information (but not these specific interviews) is available on YouTube, and on the interviewees' websites and/or in their books. The women who put the summit together, Margie Bissinger, has a great YouTube channel of her own where she posts tons of other interviews, many with the same people from the summit. Here's the link: https://www.youtube.com/channel/UC3-1i9q8ls5FbjOOVeJRW2g

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OsteoBoston on YouTube is an excellent resource too.

REPLY
windyshores | @windyshores | Feb 13 7:18am

@rogerscott8562 curious why you imply Evenity will shorten life!

One note on the topic of femoral neck: my DEXA report and my docs tell me that that score is unreliable to measure changes over time.

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