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Are you taking Reclast for osteoporosis?

Osteoporosis & Bone Health | Last Active: Feb 14 5:27am | Replies (267)

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@kirstenlheld

Did you have a slow infusion with a lower dose or was it the "regular" amount? My understanding is that the bisphosphonates work by retarding the bone breakdown effects of the osteoclasts, which would normally remove old or damaged bone as opposed to medications like Tymlos that work with the osteoblasts to actually speed up the process of creating new bone. So, what this means in effect is that if your bone density is really low, and you have a high CTX score showing that you are breaking down much more bone than you're building, a bisphosphonate may be warranted to slow down the loss of bone. If the old bone isn't removed, this will increase your bone density but that bone may not be good quality bone. However, the catch is that IF you end up having to go on a bone builder medication later, it won't work as well as it would have if it was given first BEFORE the bisphosphonate. Insurance companies usually want you to "fail" on a bisphosphonate, meaning you can't handle the side effects, etc, before they will approve coverage for a bone builder medication. What all this means is that it is not an easy decision which medication to go on first, if any, and that you may have to fight your insurance company to cover the medication that you choose.

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Replies to "Did you have a slow infusion with a lower dose or was it the "regular" amount?..."

I was on Prolia for 3 yrs before I had my Reclast Infusion. I assume it was a regular does. Took about 45 minutes. I had horrible bone pain for 2 weeks over my entire body. I couldn't sleep-still can't. I had just about every side effect they listed and it lasted for 6 months.