Indeed it is all interesting!

In the past year or so I did a blood test for genetics and it came back that I was likely to have BRCA2 mutation. With a family history (paternal grandmother died of ovarian cancer, material grandfather died of prostate cancer), my health teams feels that the BCR is "likely" because of the genetics. Figuring out how/why BCR occurs is definitely an area of interest that I plan to support.

In terms of my ADT treatment options, best to put the full discussion on the table for your consideration. After we found the cancer in 20+ lymph nodes, my doctor suggested triplet therapy (Leuprolide, Abiraterone, Docetaxel) but I was about to start a new job and didn't want to go all-in with treatment, especially the chemo (docetaxel). So, we stepped into this with a single treatment of Leuprolide and then 3 months later (PSA dropped from 19.0 to 0.4) we added Abiraterone and then 3 months later I was at "< 0.1". I've revisited the topic of chemo (docetaxel) and while my team would support if I wanted to go in this direction, their advice is to keep it in the tool kit and not use it now (and keep it available later, after it becomes resistant). So, my game plan is to finish up this 24/21 month treatment of ADT and then hopefully get off it. At age 53 this fall, my team feels that there is a "high probability of a modest recovery of my testosterone levels in 6-15 months".

I am keenly aware that every person has a different story, so my goal of sharing complete information is so that it either has matches to other people, or provides context of experiences.

keep the faith!