@bella0923
Like you, I could not tolerate the full dose at first. Headaches (bad ones), fatigue, increased heart rate. My doctor told me to dial it down to 40mcg, and I was fine on that dose. I clicked up to 50 after 1 month and then 60 about 3 weeks later. I sometimes took 1 Advil 2 hours before injection, and that helped avoid headaches the first few nights after upping my dose. I could stop the nightly Advil after a week. Last night I tried 70 mcg with no Advil, and I felt the same as I did on 60. My body just had to get used to the medication. As @windyshores said, we do expect some side effects, but the key is finding a tolerable level. Every 3-4 weeks has been a good timetable for me to bump up my dose. My body just takes that long to get used to things. In 10 days, I have my first blood test since starting on Tymlos. I’m hopeful that increasing the dose this way will prove effective.