1. < Osteoporosis & Bone Health

ReClast: Warning and Dosage Variation

Posted by njhornung @normahorn, Jan 22, 2024

I was trying to find information regarding any options of taking different dosage amounts in place of the one-size-fits-all recommended dosage. I spotted something that I cannot find now. However, I came across this warning:

Conclusion
It is important that the potential patients receive sufficient information about the possibility of side-effects following the administration of intravenous zoledronic acid. To ensure that a zoledronic acid infusion is given as safely as possible, the safety information should include that the patient should not be left without monitoring for a minimum 24 hours after the infusion. Being alone and experiencing serious side-effects may lead to acute cardiac problems.
https://jmedicalcasereports.biomedcentral.com/articles/10.1186/s13256-022-03695-y

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

sammy26 | @sammy26 | Feb 10, 2024

Thank you so much. I am thinking I need to get a second opinion at the Boston hospital I often go to for osteo and dermatology issues rather than this local rheumatologist. Even if it means delaying the treatment. I do low doses with other immunizations as well. Thank you so much.

REPLY
happyinminnesota | @happyinminnesota | Feb 11 7:46am
In reply to @windyshores "I am having a 20% dose (1 mg). One of my docs says they do this..." + (show)
@windyshores

I am having a 20% dose (1 mg). One of my docs says they do this a lot. My reduced dose is because of kidney issues, afib, and sensitivity to meds. The advice for all doses is to hydrate well (I requested IV hydration), ask for a slow infusion (up to an hour) and take tylenol before, during and after. Another thing: a 2.5mg half dose may be as effective as the full 5mg: my doc confirmed this as well.

Jump to this post

Your post is very helpful to me. I have newly diagnosed breast cancer and osteoporosis. I too am very sensitive to medication. They plan to use Reclast to counteract the Aromatase Inhibitor to fight the breast cancer, which would be horrible for the osteoporosis. I am a patient of endocrinology at Mayo and wondered which doctor do you see there that was willing to do this?
They want t start therapy almost immediately, so if you could reply soon I would appreciate it.
Bless you for publishing this.
😊

REPLY
njhornung | @normahorn | Feb 11 8:26am

You may find this article on doses helpful.

Shared files

low-dose reclast (low-dose-reclast.pdf)

REPLY
View MoreView Less
Please sign in or register to post a reply.