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Have you gone from zonisamide to lamictal?

Epilepsy & Seizures | Last Active: 1 day ago | Replies (54)
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@jakedduck1

@minajo
Although the concerns regarding Stevens Johnson Syndrome (SJS) are valid and very serious, I hope the doctor also explained it’s extremely rare especially while taking Lamictal.
Did your doctor also explain there is a genetic test to see if your at an increased risk of developing SJS? I'd definitely recommend that test if from certain Southeast Asia.
Personally, I would not hesitate taking Lamictal but it may help if you titrate more slowly to help reduce any side effects. I figured the benefits far outweigh the risks of the many seizure meds known to possibly cause SJS that I have been on over the 57 years I've had Epilepsy, not to mention all the other types of medications known to have a relationship with SJS as I imagine you have.
Take care,
Jake

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Replies to "@minajo Although the concerns regarding Stevens Johnson Syndrome (SJS) are valid and very serious, I hope..."
hopefullibrarian | @hopefullibrarian | Feb 9, 2024

My understanding is that titrating is essential when starting, and you have to be weaned off, when and if the time comes, as well.

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minajo | @minajo | Feb 10, 2024

Thank you.. i didn't know about the test! I asked epileptologist about it before we change, we just did amino acid test so doubtful dr will order..
Autism and epilepsy hard to treat,, so many drugs.. input from neuro too saying to keep Zonisamide even tho weight gain , labs bit off.. saying more risk of SJS with older AED'S so... thank you !!

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