My husband had his first Pluvicto infusion three weeks ago. By now, most of his side effects are gone. What follows is his side effect history. He had some nausea the first couple of days, but the sublingual medication Mayo prescribed made him constipated, which he hates, so he didn't take any more anti-nausea medication and took Miralax twice a day for a few days instead until the constipation eased. Luckily the nausea was mild and was gone within a few days. For a few days after the infusion, he had no appetite; by now he is hungry much of the time, but some foods don't taste quite right and others don't appeal to him at all, sohe is figuring out what to eat a day at a time. He still has some extra fatigue but has been out working in the yard a lot anyway. He has a bit of back pain after his yard work, so I am not sure if that is from the exertion or the spinal mets, but suspect it is the yard work because the pain eases when he comes inside and rests. Another note: he had his post-Pluvicto lab work (CBC and CMP) done locally yesterday. The lab faxed the results to the Kwon team at Mayo, who said his numbers are stable, meaning no worrisome effects from the first Pluvicto infusion. His second infusion is scheduled for February 28.