Is there treatment for mucinous adenocarcinoma of the prostate?

I also have mucin producing urothelial adenocarcinoma of prostate. Diagnosed last February although due to the rarity it took bone scans and pet scans and multiple path labs to confirm. I had 2 months of FOLFOX chemo which brought my CEA down some but didn’t do much to shrink tumors. ( I was stage 4 with Mets to spine, peritonium, lymph nodes and seminal vesicles). Got full genetic testing of tumor and it scored PDL-1 100 so we started Keytruda and Ivermectin. I dose the Ivermectin at 0.4mg/kg on three sequential days each week. It greatly increases the response to Keytruda. After 6 week my CEA was down to normal (2.8) and CT scan at 10 weeks showed the Mets had disappeared and prostate tumor was 1/3 the volume from initial diagnosis. Urological symptoms largely disappeared. As of now, CEA has slowly climbed to 6.2 and symptoms are slowly retuning so seeing urologist tomorrow. I also take capecitabine (Xeloda) one week on one week off, quercetin with bromalin, Lycopene and Curcumin. Those nutraceuticals can only be used with nonoxidizing chemo. Please let me know how things are going and certainly get the genetic testing.’

"The average 5-year biochemical recurrence-free survival for patients with MCP was reported to be 87.5-100% (4, 7, 14)." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786235/#:~:text=MCP%20is%20extremely%20rare%2C%20with,glandular%20tissue%20with%20extraluminal%20mucin.
Mpuap offers the best information from experience. Radiation may be available for you. You'll want more testing maybe at a larger institution where there is more familiarity with the disease.
Best wishes, readd.

Urology visit went well with no sign of recurrence in bladder or urethra.

mpuap, this really good news.

Is the Ivermectin MD prescribed or self-prescribed? I know it is used for a myriad of conditions and I am curious as to the rationale for its administration.
Thanks and good luck.

Google Ivermectin plus checkpoint inhibitors. Find the article in “Nature”. That’s the best academic article that I have read. Ivermectin increases PAK-1 degradation, Caspase 3 induced apoptosis and several other mechanisms of suppressing tumor growth and metastasis. It is FDA approved (not specifically for cancer), safe ( very favorable side effect profile), is synergistic against many solid tumors when combined with 5-FU and/or checkpoint inhibitors and a variety of other therapeutic agents. It is not a miracle cure by itself. Due to the politicalization of Ivermectin use for Covid, physicians that agree with adding it to therapy and afraid to prescribe it due to potential aggressive regulatory action. However, if you show the evidence to your oncologist and source quality Ivermectin for human use they are more likely to support your choice. There are a few trials going with Ivermectin and triple negative breast cancer but it is very difficult to get funding because this is a cheep drug and, again, political resistance at NIH. We should be doing more research on repurposed drugs for cancer as there is a preponderance of academic evidence of potential benefits to utilizing cheep old drugs to enhance effectiveness of our newer and incredibly expensive oncology drugs.

Researchers are studying Ivermectin to see if it may be used as an anti-cancer drug and early studies show promise. Please note that this research is in the early stages (mice studies) and has not yet been tested in human trials. Ivermectin is not a proven standard treatment for prostate cancer.

Ivermectin combined with other chemotherapy drugs or targeted drugs is being studied in early clinical trials and shows promise in patients for whom conventional chemotherapy has not worked in some cancer types. It may be effective against drug-resistant cancer cells.

– Ivermectin, a potential anticancer drug derived from an antiparasitic drug https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505114/

Important
It is NOT safe to take ivermectin that is commercially available. Please talk to your doctor before taking any over-the-counter medications or supplements that claim to fight or cure cancer.

If commercially available Ivermectin is NOT safe to take, why is it an approved FDA medication? Other than commercially available Ivermectin what other source is there...the local high school chemistry lab nerd?

My wording wasn't very clear, was it? Sorry about that. I mean non-prescribed ivermectin, i.e., over-the-counter ivermectin for animal use and commercially available in animal supply stores.

Medically approved ivermectin is available by prescription.

That makes it clear. I've read of folks going to the local farm supply house to purchase Ivermectin that is used for farm animals. I did not think that was what you were referencing. Even if produced in a sterile environment there is the problem of proper dosing for human use. Thanks for the clarification.