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How Long For Body To "Reset"?

Osteoporosis & Bone Health | Last Active: 3 days ago | Replies (38)

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@formisc

Thank you for your very detailed reply!

Based on your aunt's TScores, I am astonished that her doctor put her on Prolia which should rightly only be used for those at high risk of fractures and where other meds prove ineffective. It is probably fortunate that the doctor was not able to continue prescribing Prolia because there's no sure way of mitigating the rebound effect once you have been on Prolia for 4, 5 or more years

Thanks for the youtube link and the very useful pdf. I have seen another interview where Dr McCormick expressed his view that, for 3 or more Prolia shots, Alendronate is not potent enough to mitigate rebound and you would need to use Reclast (zoledronic acid). But i have read other sources that say Alendronate is ok for up to around 2-2.5 years of Prolia (see link below):
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081316/
Also, the following is a youtube video where the doctor recommends the use of Alendronate for someone who has been on Prolia for 2 years:


It's likely that your aunt's active lifestyle precluded any rebound fractures. Also, it's been speculated that treatment with bisphosphonates prior to Prolia may help in mitigating the rebound effect

Did you do any BTM labs before starting treatment to use as baseline reference? You did your zol infusion in Nov 21 and your CTX in Nov 22 is 179. But a year later in Dec 23, your CTX is 130 (?). I would have expected your CTX to go up as you were not on any other osteo med after your zol infusion more than 2 years ago

Edit: saw from your earlier posts that you did not have any baseline BTMs done and your low CTX could be due to your hypothyroidism. I agree with your assessment that anti-resorptives are probably not appropriate for treating your bones. Are you currently considering anabolics? Personally, i am cautious about any osteo med and i want to give drug-free treatment a chance

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Replies to "Thank you for your very detailed reply! Based on your aunt's TScores, I am astonished that..."

I’m with you on wanting to try natural means instead of osteo-meds. It’s what I wanted originally but like so many others, my doctor pushed me towards meds and I trusted his opinion.

I won’t rule out osteo-meds all together but I’m not sure what would have to happen to make me decide drugs were my best option. The anabolics sound like they would work better for me but those drugs are so new and there isn’t enough info about the long term side effects and that concerns me.

For now, I plan to stick with my gym routine. I recently upgraded my membership so I can use the hydro-massage and the Ergoline Beauty Angel—I didn’t name it LOL—so basically, I’m adding vibration and red light therapy to try to help my bones. No idea if either will improve my BMD but I ate 5 to 10 prunes everyday for one year to try to help my bones so, basically, I’m willing to give anything, within reason, a shot. There is research to show that both red light therapy and LIV (low intensity vibration) can help bones.

I also want to incorporate the exercises (weight lifting) the patients in the LIFTMOR study did so I’m considering working w/ a personal trainer but I can’t start that until later in the year (after I get my aunt relocated closer to me).