Unbelievable. There is a 290 mcg of the Linzess, do you think that would help? I wonder if taking something for your gut spasms such as Bentyl (Prescription) would help you? I was in a bad way with spasms after COVID and the Levsin (Prescription) for spasms caused blurred vision, but, the Bentyl doesn't and worked beautifully. I was checked for SIBO, an endoscopy was done, esophagus was dilated, found out I have a hiatal hernia....you know the drill on trying everything. I do not have POTS and this is just a thought, ok?

Sometimes later on due to COVID we may not respond to our meds & supplements like we did before. I wonder if your meds for POTS need tweaking and they are slowing down your gut now due to COVID. I know that sounds crazy....but, COVID does crazy things. Miralax never worked well for me...you definitely have to play with the dosage.

IBS-C and spasms is hard to treat. I'm so sorry you are battling this. It sounds like you are doing all of the right things, I mentioned Magnesium 200 mg, have you tried that with your breakfast? I can't take that at night when I take my Linzess or I have the other problem. I had to try many different things until I found the right thing.

Are you able to get any form of exercise at all? Walking outside even? This can help moves things along in the gut.

Are you on a good probiotic? I had to go on one after COVID. MegaSporebiotic is a good one but strong. You have to start slow. Due to my gut senstivity, my doctor switched me to ION Gut support. Gut issues are exhausting. I empathize. I am so hopeful and prayerful for you to get great improvement soon. God Bless You!