LDN resets your immune system. Mostly it is used to treat auti-immune disorders. However, they are finding more and more illnesses are auto-immune and at very least, being in pain 24/7, affects our immune systems as we will always have too much cortisol and adrenaline floating about. Fight or flight. It is best for inflammatory disorders and I'm sure, where there is pain, there is inflammation.

Remember, the lower the dose the better and begin very, very slowly. It is also said when you first go on, it can cause your systemic yeast to proliferate which will make you feel back so you will want to get on something to treat yeast overgrowth. You can google and read about that online. Not a lot of drs are aware. Our damaged colons allow yeast to hide in every pocket of our being. We must treat that as well.

Start at 0.5mg for 2 weeks, 1.0 for two weeks etc. Rarely should anyone need to go higher than 4/4.5. The higher the dose, the less it will help. Please study a lot how it functions. Its not the taking it that helps, its when the halflife gets low enough to kickstart your adrenals again (hopefully ~2 hours while you sleep) that it helps.

You want a short halflife therefore a lower dose. Ive studied and taken it for years. As a nurse, my doctor allows me to crush the 50mg tablet into 50ml of water which equals 1mg/1ml. I am right now taking 3.5 ml, 3 5 mg, at night mixed with a jigger of whatever.

Hope that helps. If you start with a huge dose or go up too fast, you might well suffer insomnia or bad dreams and want to come off. Going very slowly is the answer for success.

This is a long term decision as yoy will need to stop all opoiods. When people cintinue to take pain meds on LDN, they will get no relief and unintentional OD can occur. It could be 6 month or more before you see any benefit. Its a commitment to endure your pain for a while hoping thus will help.

Once you start, know yoy are committing to minimum 2 years. This is not a quick fix.

I've gone off for surgery (you must be off for weeks before surgery and I didn't thinj it was helping a lot till I had veen off if it for a month or more and wham. Pain back. It was indeed helping. It was just so gradual, you forget to notice.

Hope this was helpful.