My problem is mainly at night. Sometimes during the day. I started out taking them at night only but i need to take them all day to see if that i can permanently get rid of this. I bought mine at the health food store with ither stuff and i don't know what i paid for it. I need to go get more & i will see how much it is. I guess it just depends on how well it works for each person. I hope it works for you as it does me. Keep me updated.