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← Return to Evenity Side Effects
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@mayblin I do not have a P1NP during the time Tymlos was actively bone-building. I have a P1NP before treatment and two after 18 months on Tymlos. I am waiting for P1NP results after one month of Evenity and expect it to be high. This test can take weeks to come back. My P1NP's basically showed Tymlos was no longer working to build bone, but I stayed on it for maintenance for few months while deciding next steps. I had a 20% gain in spine and 9% gain in hip so earlier in treatment it was quite potent but I don't have testing for that period. Here are my results:
2/22/20 54 (ref. 16-76) this was not fasting and 10:30 am- before Tymlos
Tymlos 6/21-12/23
5/23/23 40 (ref. 16-96) fasting, 9 am
7/18/23 35 fasting, 9 am
Evenity 12/26/23
1/26/24 ???? fasting, 9 am
Evenity 1/2 dose 1/30/24
Replies to "@mayblin I do not have a P1NP during the time Tymlos was actively bone-building. I have..."
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@windyshores thanks a lot for posting your results. I've been reading and comparing yours against published data. Although your P1Np at 'peak' wasn't captured, most likely it had and the later trend fit what was described. Your CTX is a bit hard to interpret. The baseline, w/o fasting and timing factor was at 324, which could be adjusted higher presumably as your true baseline considering these factors, right? More puzzling is the drop after 2 yr tymlos. Am I reading the wrong way? Did any of your consulting doctors help you make sense of these data?
I realize that btms are not uniformly reliable among population. For some ppl they give good signals while for others the data could be so variable that it's hard to interpret. There was a physician who had a few non responding patients ended up with improved dexa.