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Methotrexate / Actemra

Polymyalgia Rheumatica (PMR) | Last Active: Feb 2 6:53pm | Replies (40)

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@prestol

It’s complicated, isn't it, when you have more than one autoimmune disease needing treatment. I must take a TNF blocker for my Crohn’s, but couldn’t also take Actemra. I am so glad it’s working well for you. It’s early in this process for me, and I guess I was hoping to hear something encouraging about Humira. Thanks for sharing your history.

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Replies to "It’s complicated, isn't it, when you have more than one autoimmune disease needing treatment. I must..."

Yes it gets complicated quickly when the immune system goes haywire. Toss in prednisone side effects, especially the one that causes adrenal insufficiency, and things get hopelessly complicated.

I wish there was a better solution than prednisone. Nothing seems very straightforward. Every alternative treatment seems like trial and error.

Maybe Humira will work for you. Nobody knows with any degree of certainty what will work when there is a mix of things going on.

I know prednisone is used short term for flares of Crohn's. With all the GI side effects from prednisone how do they expect you to take prednisone long term for PMR?