My husband is 74 years old. He has gone through many treatments that eventually stopped working. He remained on Lupron injections every 3 months consistently. He was first on dexamethasone 2 and 1/2 years, zytiga for 3 years, These were the more stable years and lower PSA levels. He had testosterone injections for a year that brought his PSA down and then stopped working. Re-tried zytiga last year but it failed. Because of the Pluvicto not being approved in the US until 2021 he waited without any treatment for 9 months. Then to have Medicare approval to try Pluvicto he had to go on chemotherapy drugs. He lost extensive weight and became very weak. This may have been the reason that when he was approved for Pluvicto he was in a weakened state and never really seemed to benefit from this treatment. I think it is going to be a life saver for many men.

My husband lived to almost 75. He died one week before his birthday.
He had not been able to receive Pluvicto early because of the hold up with the FDA approvals. He went without any treatment for 9 months. It's hard to say what might have been the outcome but he weakened greatly when he was mandated to try Chemo treatments before getting Medicare to pay for Pluvicto.
I believe that Pluvicto is the cutting edge of the treatment for the immune system, that cancer will be recognized as tied to our depleted immune system. I'm a retired RN nurse. Fred Hutchinson Cancer Center gave us 11 years and I would say 7 were very good years.Best wishes to you