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Advice/experience about going back on Prednisone
Polymyalgia Rheumatica (PMR) | Last Active: Feb 12 6:43pm | Replies (48)Comment receiving replies
Every bottle of melatonin I ever purchased had a warning not to use if you have an autoimmune disorder. PMR and GCA are autoimmune disorders. When I shared this with my Rheumatologist, he was surprised.
I just Googled this topic again, and what I found was complex and confusing.
On 40 mg of prednisone to treat GCA, I'd startle awake after two hours of sleep. I chose not to take melatonin. I got out of bed, read a book and drank lemon balm or valerian tea. After a couple of hours, I went back to bed and slept for a couple of hours.
I just read that lemon balm can interact with a thyroid medications and sedatives so use with caution.
As I tapered prednisone down to 10 mg and under, sleeping became easier.
I hope this helps.
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Melatonin is a hormone that affects a lot of different body functions, including strengthening the immune system. We're trying to suppress our overactive immune response with PMA.
The Mount Sinai website points out the benefits of Melatonin, but says:
"Steroids and immunosuppressant medications: Melatonin may cause these medication to lose their effectiveness. DO NOT take melatonin with corticosteroids or other medications used to suppress the immune system."
https://www.mountsinai.org/health-library/supplement/melatonin
In Australia, melatonin is available only on prescription in 2mg tabs. There is an exception for over 55yo who may buy one month supply from a chemist after discussing their other meds and needs. If you're on steroids you're directed to ask your doctor before taking melatonin. I'm surprised how freely available it is in some countries.