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Stopping Evenity Early

Osteoporosis & Bone Health | Last Active: 3 days ago | Replies (115)

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@windyshores

I went in for my second Evenity today and declined the second shot. The nurse said they have people stop early at 6 months, but not sooner.

Here is what I wrote elsewhere about today and my decision:

I had met with an allergist at the request of my endo. Allergist said I should pause between shots to ascertain effect before having second one. Nurse said I could only have a one minute pause. I got her to wait three. I decided against the second injection. Thigh injections are absorbed more slowly that tummy. By the time I got to my car, same burning band of tightness in mid abdomen, but more tolerable than two injections last month (which had an intense effect w/in a minute).

I read initial studies that based dose on weight. Standard dose is 3mg/kg for someone 150 lbs. I weigh 104. Essentially 3mg/kg would be about 140mg Evenity. One shot is 105mg, two shots is 210mg. Basically I got 2m/kg with one shot versus standard 3. That was reported as 1/3 less effective but still pretty good. Basically 10% increase vs 16% (see post above by @normahorn).

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Replies to "I went in for my second Evenity today and declined the second shot. The nurse said..."

Windy: Sounds like you did the right thing based on your dosage analysis. Do let us know how you do after a few days compared to your previous experience.

I think there are quite a few medications that should/need to be calibrated based on weight. Why is this not done?

The medical world seems quite aware about being careful about dosage when there are children involved but that does not seem to carry over to adults. Especially older adults.

One size usually does not fit all.

People are smart to stop at 6 mos! I asked about it but was told any muscle
And joint pain I had were not related and I wasn’t proactive enough to stop.