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Evenity and heart

Osteoporosis & Bone Health | Last Active: Aug 10 11:04am | Replies (36)

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@jenx68

Hello. I saw one of your comments from several months ago and I have some questions if you don't mind. I was just diagnosed with what my doc says is severe osteoporosis, although its not as bad as some of what I've seen here. Mine is -3.4 spine, and -2.5 and -2.6 at hips. I was reading about your experiences with Tymlos and now Evenity, and those are the meds I need to quickly choose from. Like you I have heart issues, i.e., heart attack with stent placement, and a DVT at a different time, but both were a few years ago. I have CHF that is not as well controlled as i would like, and suffer from painful racing and pounding heart.
And as a long-term result of the heart issues, I now have kidney disease, with eGFR in the high 30s to mid 40s. I'm finding that I'm terrified of both these meds, at least as related to my cardio side effects. How long did it take you to adjust your Tymlos dose to avoid the tachycardia? With Evenity are there any noticable cardio side effects, or are the potential serious cardio side effects silent? And is one or the other harder on your kidneys? Another issue I'm facing is that I'm not able to stop some of the meds I take that make osteoporosis worse. I have COPD and must use a corticosteroid inhaler; and I take loop diuretics for the CHF that I must continue (can't take thyazides). So whatever med I take is going to have to fight to work as well. Goodness, that's a lot. My apologies. Guess I'm just feeling overwhelmed. And its just me, so I have to be able to manage whatever I'm taking enough to be able to function. Any info. you have, or experiences you or anyone else have had will be helpful and greatly appreciated.

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Replies to "Hello. I saw one of your comments from several months ago and I have some questions..."

@jenx68 it would seem you are a good candidate for Tymlos, which is very effective for spine. I have afib with tachycardia and didn't have heart issues with Tymlos. Yes heart could speed up a little very briefly, but I hydrated well and that seemed to help (I have low bp).

I am not a doctor but the Evenity site seems to say if you have a history of heart attack or clot, it might not be the best drug. It is hard because cardiologists don't know bones and endo's don't know heart!

Neither drug affects kidneys. My GFR is also in the 30's and 40's (but Cystatin C is a little higher).

It would seem Tymlos is the better path for you but ask your docs!