My daughter in-law has had two surgeries at Mayo in Rochester the last two years for pituitary tumor/acromegaly. Both surgeries were done through the nose. Due to the tumor being extremely close to an artery, the tumor could not be completely removed during the first surgery. Radiation was going to be considered for remainder of tumor, however tumor grew back within six months, so surgery had to be repeated. She received radiation about three months after the second surgery in 2019 and to this date is doing well and tumor has not grown back. Recovery from both surgeries was without any major difficulties, other than headache, that I believe is common and to be expected.