Regarding "flaring" and when to expect it on the 14-day regimen–– My dermatologist had given me her OK to divide my bald head into two sectors: rear and front. I started applying the fluorouracil to the rear one day, then on the front six days later. The sectors showed not much signs of flaring, not until each sector's Day 10 or 11. I'm not done with applying the fluorouracil to either sector and watching to see how all spots of evidence of flaring gradually fade.