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← Return to Methotrexate / Actemra
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Polymyalgia Rheumatica (PMR) | Last Active: Feb 2 6:53pm | Replies (40)
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I am on 5mg of prednisone and 10 mg methotrexate and trying to get off prednisone. I have thought that methotrexate helped with few if any side effects for me. But the problem of profound weakness with cutting back on predn below 5 has me concerned. Does anyone have any ideas?
Replies to "I am on 5mg of prednisone and 10 mg methotrexate and trying to get off prednisone...."
I wouldn’t presume to second guess your Rheumy. But what I will add is that when MTX is used with RA biologics they tend to work more effectively in combination than either drug does alone. I’m not sure if that’s true with MTX and Prednisone.
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I'm been on the same combination for 5 months and am not able to go lower on the pred. The impression I get from my rheumatologist is that as long as my labs look good he is comfortable keeping me on these doses indefinitely. At my last appointment he brought up Kevzara as being the next option if labs or side effects aren't good. I don't have a good solution for you or myself. I have decided that I just need to be patient and take care of my health the best I can.