So just to share progress so far today:

My endo called me last night and ordered CTX and P1NP and I made a lab appt. for tomorrow, fasting. He does not usually do these tests and explained that they don't tell us everything that is going on with bone. (McCormick and my other endo do rely on them with caveats.)

I got a cancellation appointment with an allergist today (I really like him, used him before) and he does not think my immediate reaction of abdominal tightness after Evenity was an allergy. He said side effects can in fact happen quickly and also that the monoclonal antibody rososozumab (Evenity) is a large molecule/protein and the body may not recognize it (18% of us develop antibodies by the way, that do not affect effectiveness). So there could be a sort of reaction that is not allergy, but it could also be a side effect. He suggests doing shots in thigh, pausing between, and doing injections in a hospital office where I can be monitored.

The reaction I had was this intense tightness (felt hard to breathe) below the diaphragm for 4 days with some tingling of hands and feet- after the shot. In the last two days it has come back more, even though I had the shot on Dec. 26th. Last night my daughter slept in the room with me and said I was distressed in my sleep and breathing deeply and very fast and I woke up feeling unable to breathe. It was just my chest tightness. My lungs were fine,

But guess what? I am inclined to do Evenity again regardless. I feel like this is my last chance for full effectiveness of bone builders though they will still work 50-60% after Reclast. Tymlos gave me huge gains but my femur neck is still -3.6 (more cortical and Evenity helps with that- Reclast may too, I need to find out). Question is, how much should I endure in terms of side effects for how much gain?

On Tuesday I see a second endo who does rely on CTX and P1NP and does them frequently. I will discuss side effects with her. I can check just about every one on the list! Next Evenity is scheduled for Thursday. In the meantime I am trying to schedule Reclast in case I decide to do that now instead. Whew!