← Return to Stopping Carvedilol (Coreg): When will the effects wear off?

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@nelle49

I have been taking 50 mg (2 -25 mg TID, 1 -40 mg Telmisartan and 6.25 HCTZ for about five years. I’ve gotten my Blood sugar normal thru low carb diet, lost weight (eating at home for months) and exercising more. My BP came down dramatically. My doctor has been weaning me from Carvedilol for weeks. From taking half for two weeks, to 1/4 for two weeks to 1/8 for two weeks. She was mostly worried about my pulse going up. And it has been somewhat faster. High 70s low 80s. This week she had me stop the 3.125 TID. I only took the 3.125 at night for 3 nights then 3 nights ago stopped it. So no Carvedilol for three days. I’m not happy with my pulse. E.g. sitting here it’s 89. If I go up one flight of stairs it will be 115. If I walk into another room it’s 105. I get a little out of breath. No heart disease that I know of. The pulse does come back to the 80s quickly when I sit. Will this adjust and come down to high 70s low 80s or should I call her and see if I should go back on at least one 3.15 once a day? Or is there another beta blocker that’s milder than Carvedilol. My blood pressure is still very good. Seldom over 120/80 and usually more like 110-115/70.

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Replies to "I have been taking 50 mg (2 -25 mg TID, 1 -40 mg Telmisartan and 6.25..."

Hi @nelle49, welcome to Mayo Clinic Connect. Congratulations on effectively managing your blood sugar with proper diet and exercise and getting your blood pressure under control. I'm sorry to hear about your current issue with your elevated pulse due to the Carvedilol tapering. @ashby1947, @wigreenthumb, @predictable, @fireguy8891, @rois4richo and @jfperrone have all used or currently use Carvedilol and I invite them to share their experiences with you.
Did you decide to contact your physician? If so, did she recommend anything?

Hi, Nelle (@nelle49), I'm responding to Amanda's invitation to share my experience with Carvedilol. Your medication was almost identical to mine before you began phasing down Coreg -- 50mg in two doses daily, 40mg of Lisinopril (a cousin of Telmisartan), and 10mg of a diuretic (mine is Amiloride). I'm also taking Coumadin (5mg) and Atorvastatin (10mg), but they're not relevant to my blood pressure or pulse rate. Overall, I don't find your pulse rate -- including its rises during exercise -- to be much different from mine, even though it has risen as your dosage of Coreg has been reduced. Your wise choice of scaling Coreg down over time with guidance from your doctor was a smart move. I'm not into that, because my BP remains steady at the top of the recommended maximum for people my age (85). I'd give a buck to be able to reduce (or change) my BP meds, but that's not in the cards. Your situation probably differs from mine and is well understood by your doctor, but since you're concerned about it, you might benefit from an exchange of views in a personal discussion with your doctor. Anxiety is an important symptom of hypertension and deserves to be addressed as much as your physical readable symptoms. A steady daily exercise regimen is another objective of my medical team (which includes me). And we periodically discuss whether and how to change my medication. Over the past 25 years, my doctors have prescribed a variety of 12 different meds, and I have acquiesced because the changes were upgrades to match changes in research results. I hope you and your doctor can move into a state of stability and comfort with minor adjustments indicated by your situation. Martin