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Evenity Side Effects

Osteoporosis & Bone Health | Last Active: May 20 11:26am | Replies (227)

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@windyshores

I talked with my endo and with McCormick today and made an appointment with another endo who does do CTX and P1NP tests. I also made an appointment with an allergist to discuss what might have caused my reaction to Evenity since noone thinks it was the Evenity itself (probably the polysorbate 20 preservative, to which I already knew I was sensitive). I will get CTX and P1NP tomorrow- I got three providers to order it today as it happens, since I talked to so many people! All of this happens in the next 6 days and then I will put it all together and decide whether to do a second Evenity or start Reclast.

McCormick and endo differed on whether starting Reclast with a lowish CTX is going to do anything (endo says mine runs low anyway). CTX was 324 before Tymlos and at the end of Tymlos was 186. There is no issue with transition to Reclast despite my probably low CTX.

Endo said that Tymlos does not worsen cortical porosity (another question I had) but Forteo does. Evenity addresses femur neck cortical bone more than Reclast. Both docs agree that after Reclast, effectiveness of bone builders will be less (but still helpful) so Evenity first is kind of my last chance at getting maximum effect.

If I choose a second dose of Evenity, I need to do it quickly so getting all this done fast! Cancellations helped me with all docs today.

I got some differing opinions today and probably another viewpoint next week. I often have this experience. In the end, I guess I kind of collect opinions, cross reference them and still have to decide myself! I don't want anyone to make decisions on what I am posting here since I am getting different info from different providers and without citation !!

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Replies to "I talked with my endo and with McCormick today and made an appointment with another endo..."

Hey Windy. Thinking of you going through all of this sorting out within a very short timeframe. If anyone can do it, it is certainly you.

Just one thought: if the allergist confirms the issue is/could be the polysorbate, I hope there is some way to neutralize that so that Evenity can continue. I would not rule out even considering some sort of Asian approach, like from an acupuncturist.

Best of luck.

@windyshores I found it's interesting that your CTX level at end of tymlos. Was there a trend of decline over the course of tymlos treatment? 186 would place you among the normal range among the normal population. If you repeat CTX this time and came back at this similar level, I wonder how low reclast will push it down, understand that you will be doing partial dose. Is there a 'target' that your endo is shooting for, to maximally preserve the precious gains that you've gotten?