When i first Linzess I had horrible diarrhea. I ended up in the hospital with dehydration the week of daughter's wedding. If you keep taking Linzess the diarrhea will get better. Then it stopped working so now I add other stimulants. Prunella (?) somebody mentioned which is good. Trying to figure the best thing to do with colonic inertia. Colace with Senna etc etc. Every where I look on line says "NO" to total colectomy with or without ileostomy. Mine would be with ileostomy. My gastroenterologist "dismissed" because he said I need the surgery.
Any health provider that is gastro, urogynecologist, will say surgery from my experience in Florida. My internal medicine doctor (who referred me to gastro) was shocked, as well as my pelvic floor therapist and myofacial release provider.