Hi, @tgagnier. Welcome to Mayo Connect where patients like yourself gather to talk over their medical experiences and share how our experience relates to yours. I was interested in your prescription for Nifedipine at 60mg per day. I also was on calcium-channel blockers about 15 years ago, but at a smaller dosage, and my doctor took me off or it for its tendency to leave fluid in my lower legs and feet. Besides, I didn't then have the heart rhythm problems that calcium-channel blockers also address. When I developed Atrial fibrillation four years ago, my medical team put me on Carvedilol as the main medication for stabilizing my heart rhythm and reducing my blood pressure. In this case, my dosage is 25mg of Carvedilol twice a day. What is your Carvedilol dosage? FYI, it struck me that your Nifedipine dose is pretty large, given that you also are taking Carvedilol. Together, those two drugs pile on a lot of side effects, as you can see at these web sites: rxlist.com/coreg-side-effects-drug-center.htm and medicinenet.com/nifedipine/article.htm.

With the information these web sites provide, you'll be equipped to have a detailed conversation with your doctor about why s/he prescribed each of the medications, why you need them both, why the dosages are so high, and how you can combat the side effects of anxiety, tiredness, lethargy, and depression. Will you be able to get an appointment with your doctor for these purposes?