@mikee2all, Just over 3 years on Tagrisso. No recurrence. My Oncologist plans on continuing until the negative side effects become unbearable. No major negative side effects to date. In fact, he's stopped ordering MUGA scans because my ejection fraction has gone up! The diarrhea stopped after 6 months or so. I never had skin problems.

I'm 63-years-young, walk 3+ miles outside every day. Weight-lifting (bands) 2 or 3 times a week. PT almost every day. Eat a primarily Mediterranean diet. Still working full-time. Life is good!