Don't be discouraged @randypape. The body reacts gradually to a change in Coreg dosing. Four days is like overnight. Fourteen days experience is a good period to guage your response. Why do you think the medication is responsible for faster heart rate with sweats and slight back aches from walking exercise? Can you talk this over with a cardiologist?

@predictable The body does react slowly. Fourteen days is rather fast to clear out Coreg and its effects. The time it is still active in the body can be as long as 30 days, so must be tapered off very slowly. Coreg suppresses the heart rate severely and so an elevated heart rate while exercising is quite normal as the heart must work harder to deliver the needed oxygen to the muscles using it while exercising.

I agree @eileena. I was thinking of 14 days for accommodating a reduction in Coreg dose from 25mg per day to 12.5 per day. Clearing Coreg out altogether would probably take longer -- maybe six weeks.

@predictable I am on a 3.125 X2 dose. When my Cardio agreed to removal of the coreg he wanted me to go directly off the stuff. Migraines came back within 2 weeks. Next he told me to take half the dose, they came back in 5 days. I have been slowly weaning off (1 less dose per week) for the last 4 weeks and have had absolutely no effects, negative or positive. This is why it is so very important to do this very slowly. It is probably as bad a drug as Amioderone which was never tested by FDA, but was backdoored after it first gained popularity in Europe, then South America and then was introduced here.

AND...25 mg/daily is a very high dose compared to what I take, altogether 6.250mg split into 2 doses of 3.125.

@eileena my experience is a contrast to yours. My nephrologist started me on 6.25x2 daily dose, largest recommended by the FDA as a starter. Over several months, the dose was gradually increased to 25x2 daily, where I have been almost a year. I have had mild symptoms of the kind you and others report, although never a headache. Even when I miss a 25mg dose in the evening, I don't recognize any special symptoms; I attribute that to the carryover that is common from Coreg and is the reason for gradually adjusting dosage to allow the body to accommodate revised levels. My heart rate has stabilized around 80 bpm compared with a pre-afib rate of 50 bpm. I think a lot of the bad vibes people get from Coreg can be traced to prescribers who don't take time to recognize the outspoken advice from the FDA and the manufacturer to always change the dosage gradually and never drop it abruptly from any level other than your 3.125mg.

@predictable my cardio put me on the lowest dose 2X daily. I am not sure why, but it could be his extreme caution about many things. Except for the low heart rate I have experienced for the last 2+ years and the restart of the migraines when I attempted to wean off the coreg in the past I have had no problems. He also has me on a very small dose of Losartin 25 mg as my BP fluctuates quite a bit during the day. My GP has me on a very small dose of Levothyroxin as well as my response to it, dropping from a 27 TSH to a 3.15 with just that small dose, caused that doc to also err on the side of caution.

They are just very cautious except for when they did the quad bypass, there they went full out. Prior to my ablation in 2015 I had up to 20 PVCs a minute, now I get none.