I am 73 and had 4-3 in 2 cores and 3-4 in 2 cores all from the area of the 7mm lesion out of a 30 core transperineally biopsy because of my 210 gram prostate. I did the 5 proton treatments at Mayo Phoenix and finished 4/17/2023. I was also on Androgel since 2008 but in my case my endocrinologist had taken me off my Androgel a few years back to see what my system was generating on its own for a month. I was castrate! I also experimented on my own during regular blood work and found that after 60 hours without the gel I was also castrate. I told my radiation oncologist this but he wanted to jab me with Lupron so bad he could taste it and I refused his generous offer. He tested me after I stopped the gel even though studies show that for men over 70 there is no difference in OAS and BCF if you don't do ADT. He tested me and my testosterone level was under 12 ng/dl which is lower than the Lupron shot promises. I tested twice more out to 8 months, and I was still under 12ng/dl. when I restarted my Androgel. My urologist tested all my pituitary hormones, and they were all on the money. They were sending all the signals, but the boys were not answering the call after being off duty so long. I am no doctor, but I would suspect you might not have needed the drugs to suppress your testosterone if your system acted like mine. My 3- and 9-month PSA's were both undetectable. I am hoping that continues because studies show that there is less chance of a reoccurrence if your PSA is very low right away. My PSA when my cancer was discovered was 2.9. Best of luck to you and have a long life.