Awfultruth, I couldn't agree with you more. I was on Evenity for 6 months and had side effects that included brain fog, fatigue, random muscle spams and, worst of all, a significant spike in blood pressure 3 to 4 days after the injections. I forgot to mention headaches. Because of the 2 week half life, your body never completely gets rid of Evenity before it's time to get the next dose. It makes sense that side effects will increase over time for those who are sensitive. The clinical trials were done with 2 injections. I'm sure Amgen will never approve a 1 injection dose since they have no data regarding its effectiveness. If they did, I would be open to another try.