← Return to My Gleason score is 7 - 3+4. How long can I live without treatment?

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@bobbygene

I have a 3+4 and a 4+3 what does it mean?

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Replies to "I have a 3+4 and a 4+3 what does it mean?"

Gleason scores are assigned to biopsy results and they are reported as 2 numbers.
The first number being the most prevalent cancer grade and the second number being the second most prevalent cancer grade.

So 3 + 3 equals Gleason 6
3 + 4 = 7
4 + 3 = 7, but indicates more aggressive cancer because the predominant cancer found was a Gleason 4.

My final postop biopsy results were Gleason grade 9 ( 4+ 5).
I also had a number of Gleason 8s (4 + 4).

Prostate Cancer is graded on your highest score, so I am considered a Gleason 9, which is in the aggressive category 8 - 10.

Best wishes,and I hope that this is helpful.

Because the first score indicates the most common grade of cell in the sample, a 4+3 moves you from intermediate favorable to intermediate unfavorable, a change that would lead most clinicians to recommend against active surveillance, leaving you to consider more immediate treatment options. Generally the recommendation in this range begins with radical prostatectomy, because you have significant cancer in the prostate, but a good chance of removing the existing cancer before it spreads beyond the prostate.
However, since a good number of clients do not like RP, there are other treatment options, most of which involve ablation--killing the cancer in place, with radiation or some other strategy. Radiation is not really clinically preferable, so the search continues for something better than both existing forms of ablation and existing forms of RP.
[I've tried to be fair and inclusive here, but emotions do run high among clients, and ambitions to do better run high among clinicians.]