I stayed on my Azsulfadine and added LDN. Just one capsul a day at bedtime so hardly noticed. Where it helped me the most it seemed was my small intesine which was full of small ulcers (looked like blisters) that Entacort barely help.. It took maybe 6-8 weeks to completely heal and I tapered off entacort. I stayed on the azsulfadine until my rheummy (in '23)suggested I try going off of it so I did. No symptoms. I was eating very carefully so tried experimenting with some of my favorites that I had been avoiding. Results so far: raw celery with veins removed - yes, carrot and rasin salad- no. Still no ASA or anything but LDN for my gut. Still eliminate high fiber foods or stay near a bathroom. No real pain, just goes straight through me in a short time.
LDN is worth reading about and finding a doc who is familiar with it. I had to bully my current rheummy to perscribe it but the first two rheummies were fine with it. Exceptance varies in the medical community.
I have had no experience with biologics of any sort so can't speak to that. I know diclofenic (Voltaren) is an Nsaid that is very hard on your gut. It would give you problems eventually no matter what. Best wishes.