@pinktower , My gosh, it sounds like you have really been through it! I hope you are feeling better from your Crohn’s episode. I know that was no fun. About starting on your meds; I have heard that some doctors have recommended that you introduce each antibiotic a week apart. That way, if you have a bad reaction to one, it will be easier to pinpoint which one it is. Members have written that Rifampin was hard on their stomachs, it worked out best for some if they took it on an empty stomach. It has been known to cramp the stomach or cause nausea. Everybody is different, you may not have any trouble at all with it. Let us know how you do on the BIG 3.