Primary Sclerosing Cholangitis (PSC)

Welcome to the online home of the Chris M. Carlos and Catherine Nicole Jockisch Carlos Endowment for Primary Sclerosing Cholangitis (PSC). Thanks to support provided by this endowment, dedicated Mayo Clinic investigators and their teams are making strides to better understand and treat PSC patients, with the ultimate goal of developing a cure for this disease.

Follow the PSC page and stay up-to-date as we post news about advances in PSC research, clinical trials, and available resources.

Dec 30, 2019

Liver Stiffness is Associated with PSC Outcomes

By Konstantinos N. Lazaridis, M.D., @klazaridis
20919-01-31 Liver Elastography
In a recent paper, published in the Journal Clinical Gastroenterology and Hepatology, Eaton et al., found that measuring liver stiffness of patients suffering from PSC is associated with outcomes of the disease. "Monitoring liver stiffness with magnetic resonance elastography has prognostic value. Both baseline liver stiffness and changes in liver stiffness over time are associated with hepatic decompensation (i.e., failure of the liver). However, changes in liver stiffness are typically slow to occur unless advanced fibrosis is already present" Dr. Eaton said. This is the largest study of magnetic resonance elastography on PSC patients and introduces the utility of such non-invasive testing in future clinical trials of these patients.
Read the paper  from Dr. Eaton
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