Gastroenterology & GI Surgery

Welcome to the Mayo Clinic Gastroenterology & GI Surgery Page! With one of the largest group of digestive disease specialists in the world, Mayo Clinic has been recognized as the nation's best Gastroenterology & GI Surgery hospital by U.S. News & World Report. Follow the page to learn about clinical trials and up-to-date research, and find resources for all your gastroenterology needs. Our goal is to connect you to others, and become informed decision makers; so post a comment, share your story, own your health.

Apr 12, 2019

Perianal Fistula in Crohn’s Disease

By Kanaaz Pereira, Connect Moderator, @kanaazpereira

Perianal fistulas are a common, disabling complication of Crohn’s disease. Symptoms include severe pain, fecal incontinence, drainage of pus, and reduced quality of life. Despite significant advances in the treatment of inflammatory bowel disease (IBD), the treatment of perianal fistulas remains a challenge.

Anti-tumour necrosis factor (anti-TNF) biologic therapies, infliximab and adalimumab have been shown to be effective treatments in healing fistulas in adult patients with Crohn’s disease. In this video, Dr. Michael Stephens discusses two studies – IMAgINE 1 & IMAgINE 2 – which concluded that adalimumab treatment led to improvement and fistula closure within 12 weeks in children and adolescents with Crohn’s disease.

Dr. Stephens also talks about new approaches and techniques being studied by researchers at Mayo Clinic, which hold promise for a better outcome in treatment of perianal fistulas.

Meet other people talking about complications of Crohn’s disease, including perianal fistula, on Mayo Clinic Connect. Join the conversation, share experiences, ask questions, and discover your support network...


Liked by Lisa Lucier

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