I take vyvanse 70 mg in AM for brain fog of fibromyalgia and fatigue. It helps on both clarity for me as well as a bit of energy. At night I use medical marijuana which makes me munch out. So weight loss is negligible. I do think it helps although my body has gotten use to it and not as effective as initially. I take a lot of other drugs and haven’t seen any reactions. I wish you good health!