Hi there…was going to write you yesterday but had a internet connection issue. The side effects really snuck up on me. It was not until I was on the 100mg dose that I really started noticing them. But, it all started to make sense to me when I realized that I had been having them for quite some time but the higher dose just accentuated them. I lost all desire to do anything, and like you my appetite was out of control! I felt like just a slug and my emotions became non-emotional. My BP was slightly elevated but my cardiologist put me on a med. My brain suffered also. Those and with the heavy sweating, it was taking a toll on me. I became so desperate to get off of Pristiq because the damage it was doing to me physically, emotionally and mentally. I am now back to myself and am working out at the gym to get back into shape. I already was overweight but the extra 20# I gained made things worse. The medication is not monitored enough by the docs that are prescribing it. For me I feel that all of the medications for depression are just plain bad. We all want the quick fix, and yes depression is a real medical problem, but all doctors need to monitor the long term issue with the medications. It is like a whiplash effect. The longer you are on them the more it screws with your brain chemistry. So I am choosing to never be on them again, and I am finding ways to cope without drugs. For me personally, depression will always be there but never will I ever let a drug company almost destroy me the way this one did. How beneficial is a drug that makes you stop living life? Let me know how you are doing, I am feeling your anxiety of going off but you can do it! Your happy self will come back and we are all here to support you!