Hi Darlia- I know you posted this 2 years ago- but I'm just seeing it now. How are you doing with the IEM? I have had an endoscopy and esophageal motility test which shows that my lower esophageal sphincter is "tight as a drum" said the doctor. So, I am on 40 mg Prilosec in am and 240 mg Diltiazem- which is a calcium channel blocker and somewhat relaxes the LES. And, then I take 300 mg of Ranitadine at night. The meds are helping- but it has been 7 years like this now.- and still feels like there is something stuck in my throat. I also know the proton pump inhibitors do something to the Intrinsic Factor- which produces Vit B12. My sister has to give herself a Vit B12 shot every month. Does anyone have any thoughts or comments on this?