I guess that I am one of the fortunate ones that it didn't take all that long (about 6 months) to find a combination of medications that work for me. I also very actively use CBT techniques to deal with negative thinking, and I think I wouldn't be able to be as functional as I am without it. I am tapering the medication I use for anxiety, as it was giving me brain fog and making me very tired in the afternoons. Today I'm taking 20mg of Lexapro and 5mg of Abilify, and that doesn't affect my energy detrimentally. When things were very bad for me I wasn't engaged in much activity, either. After being able to engage in work, which I was off for two years, with managing my sleep better, I have improved my verve quite a bit: I think it's important to be doing something meaningful for me within the limitations that I face today.