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Jul 16, 2011 · Need help with Mystery Illness--Possible Sjogren's Syndrome?? in Autoimmune Diseases

From personal experience and diagnosis, the key may be low sodium as you stated you felt better on saline IV–This is key to the beginning of Cushing’s Syndrome or Addison’s. Check out the symptoms of each. Each have to do with excretion of cortisol (either high or low) can zap you of you sodium/electrolyte balance and bring on fatigue(crushing fatigue) and brain fog. A good endocrinologist should be able to pick up on this. Both diseases are rather rare–and many times just aren’t considered. Hope this helps as I suffered for 8 years before getting a diagnosis.