I realize your post is a couple of years old, but we are desperate for answers. The description of your daughter mirrors the experience my 14 year old granddaughter is having currently. She was seen by Dr Fisher at Mayo Clinic 6 months ago but symptoms are very slow to diminish. My granddaughter is an honors student and is involved in various activities including band, piano, hockey, scholastic competitions and student council. She tries to stay engaged in her life and is currently seeing a therapist to deal with the depression. You are right when you say friends and family don't understand. My daughter and granddaughter feel very alone in this struggle. I would appreciate any information on how your daughter is coping now and any suggestions to help us. Thank you.